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Publication list from 2012 to 2016



Antigny, F., Hautefort, A., Meloche, J., Belacel-Ouari, M., Manoury, B., Rucker-Martin, C., Pechoux, C., Potus, F., Nadeau, V., Tremblay, E., Ruffenach, G., Bourgeois, A., Dorfmuller, P., Breuils-Bonnet, S., Fadel, E., Ranchoux, B., Jourdon, P., Girerd, B., Montani, D., Provencher, S., Bonnet, S., Simonneau, G., Humbert, M. and Perros, F.
Potassium Channel Subfamily K Member 3 (KCNK3) Contributes to the Development of Pulmonary Arterial Hypertension
Circulation (2016) 133, 1371-1385.    abstract

Algalarrondo, V., Antonini, T., Theaudin, M., Chemla, D., Benmalek, A., Lacroix, C., Castaing, D., Cauquil, C., Dinanian, S., Eliahou, L., Samuel, D., Adams, D., Le Guludec, D., Slama, M. S. and Rouzet, F.
Cardiac Dysautonomia Predicts Long-Term Survival in Hereditary Transthyretin Amyloidosis After Liver Transplantation
JACC Cardiovasc Imaging (2016) 9, 1432-1441.    abstract

Ben Salem, I., Boussabbeh, M., Da Silva, J. P., Guilbert, A., Bacha, H., Abid-Essefi, S. and Lemaire, C.
SIRT1 protects cardiac cells against apoptosis induced by zearalenone or its metabolites alpha- and beta-zearalenol through an autophagy-dependent pathway
Toxicol Appl Pharmacol (2017) 314, 82-90.    abstract

Berthelot, E., Montani, D., Algalarrondo, V., Dreyfuss, C., Rifai, R., Benmalek, A., Jais, X., Bouchachi, A., Savale, L., Simonneau, G., Chemla, D., Humbert, M., Sitbon, O. and Assayag, P.
A Clinical and Echocardiographic Score to Identify Pulmonary Hypertension Due to HFpEF
J Card Fail (2017) 23, 29-35.    abstract

Bobin, P., Belacel-Ouari, M., Bedioune, I., Zhang, L., Leroy, J., Leblais, V., Fischmeister, R. and Vandecasteele, G.
Cyclic nucleotide phosphodiesterases in heart and vessels: A therapeutic perspective
Arch Cardiovasc Dis (2016) 109, 431-443.    abstract

Bobin, P., Varin, A., Lefebvre, F., Fischmeister, R., Vandecasteele, G. and Leroy, J.
Calmodulin kinase II inhibition limits the pro-arrhythmic Ca2+ waves induced by cAMP-phosphodiesterase inhibitors
Cardiovasc Res (2016) 110, 151-161.    abstract

Courbebaisse, M., Mehel, H., Petit-Hoang, C., Ribeil, J. A., Sabbah, L., Tuloup-Minguez, V., Bergerat, D., Arlet, J. B., Stanislas, A., Souberbielle, J. C., Le Clesiau, H., Fischmeister, R., Friedlander, G. and Prie, D.
Carboxy-terminal fragment of fibroblast growth factor 23 induces heart hypertrophy in sickle cell disease
Haematologica (2016)    abstract

Gerbaud, P., Ferreira, F. and Pidoux, G.
[Role and regulation of cAMP signaling in human trophoblast fusion]
Biol Aujourdhui (2016) 210, 139-151.    abstract

Lecarpentier, E., Atallah, A., Guibourdenche, J., Hebert-Schuster, M., Vieillefosse, S., Chissey, A., Haddad, B., Pidoux, G., Evain-Brion, D., Barakat, A., Fournier, T. and Tsatsaris, V.
Fluid Shear Stress Promotes Placental Growth Factor Upregulation in Human Syncytiotrophoblast Through the cAMP-PKA Signaling Pathway
Hypertension (2016) 68, 1438-1446.    abstract

Pedroso, D., Nunes, A. R., Diogo, L. N., Oudot, C., Monteiro, E. C., Brenner, C. and Vieira, H. L.
Hippocampal neurogenesis response: What can we expect from two different models of hypertension?
Brain Res (2016) 1646, 199-206.    abstract

Piquereau, J., Moulin, M., Zurlo, G., Mateo, P., Gressette, M., Paul, J. L., Lemaire, C., Ventura-Clapier, R., Veksler, V. and Garnier, A.
Cobalamin and folate protect mitochondrial and contractile functions in a murine model of cardiac pressure overload
J Mol Cell Cardiol (2016) 102, 34-44.    abstract

Prola, A., Silva, J. P., Guilbert, A., Lecru, L., Piquereau, J., Ribeiro, M., Mateo, P., Gressette, M., Fortin, D., Boursier, C., Gallerne, C., Caillard, A., Samuel, J. L., Francois, H., Sinclair, D. A., Eid, P., Ventura-Clapier, R., Garnier, A. and Lemaire, C.
SIRT1 protects the heart from ER stress-induced cell death through eIF2alpha deacetylation
Cell Death Differ (2016)    abstract

Sabourin, J. and Allagnat, F.
Store-operated Ca2+ entry: a key component of the insulin secretion machinery
J Mol Endocrinol (2016) 57, F35-F39.    abstract

Sirol, M., Gzara, H., Gayat, E., Dautry, R., Gellen, B., Logeart, D., Soyer, P., Vicaut, E. and Mercadier, J. J.
Comparison between visual grading and planimetric quantification of microvascular obstruction extent assessment in reperfused acute myocardial infarction
Eur Radiol (2016) 26, 2166-2175.    abstract

Torrente, A. G., Mesirca, P., Neco, P., Rizzetto, R., Dubel, S., Barrere, C., Sinegger-Brauns, M., Striessnig, J., Richard, S., Nargeot, J., Gomez, A. M. and Mangoni, M. E.
L-type Cav1.3 channels regulate ryanodine receptor-dependent Ca2+ release during sino-atrial node pacemaker activity
Cardiovasc Res (2016) 109, 451-461.    abstract

Vettel, C., Lindner, M., Dewenter, M., Lorenz, K., Schanbacher, C., Riedel, M., Lammle, S., Meinecke, S., Mason, F. E., Sossalla, S., Geerts, A., Hoffmann, M., Wunder, F., Brunner, F. J., Wieland, T., Mehel, H., Karam, S., Lechene, P., Leroy, J., Vandecasteele, G., Wagner, M., Fischmeister, R. and El-Armouche, A.
Phosphodiesterase 2 Protects Against Catecholamine-Induced Arrhythmia and Preserves Contractile Function After Myocardial Infarction
Circ Res (2017) 120, 120-132.    abstract

Wagner, M., Mehel, H., Fischmeister, R. and El-Armouche, A.
Phosphodiesterase 2: anti-adrenergic friend or hypertrophic foe in heart disease?
Naunyn Schmiedebergs Arch Pharmacol (2016) 389, 1139-1141.    abstract

Wang, Z., Liu, D., Varin, A., Nicolas, V., Courilleau, D., Mateo, P., Caubere, C., Rouet, P., Gomez, A. M., Vandecasteele, G., Fischmeister, R. and Brenner, C.
A cardiac mitochondrial cAMP signaling pathway regulates calcium accumulation, permeability transition and cell death
Cell Death Dis (2016) 7, e2198.    abstract

Zhai, K., Gu, L., Yang, Z., Mao, Y., Jin, M., Chang, Y., Yuan, Q., Leblais, V., Wang, H., Fischmeister, R. and Ji, G.
RNA-binding protein CUGBP1 regulates insulin secretion via activation of phosphodiesterase 3B in mice
Diabetologia (2016) 59, 1959-1967.    abstract


Wang, Z., Nicolas, C., Fischmeister, R. and Brenner, C.
Enzymatic assays for probing mitochondrial apoptosis
Methods Mol Biol (2015) 1265, 407-414.    abstract

Van Berendoncks, A. M., Stensvold, D., Garnier, A., Fortin, D., Sente, T., Vrints, C. J., Arild, S. S., Ventura-Clapier, R., Wisloff, U. and Conraads, V. M.
Disturbed adiponectin - AMPK system in skeletal muscle of patients with metabolic syndrome
Eur J Prev Cardiol (2015) 22, 203-205.    abstract

Seah, S., Low, I. C. C., Sachaphibulkij, K., Kroemer, G., Brenner, C. and Pervaiz, S.
Activation of surrogate death receptor signaling triggers peroxynitrite eependent execution of cisplatin resistant cancer cells
Cell Death Diff (2015) in press.   

Ruiz-Hurtado, G., Li, L., Fernandez-Velasco, M., Rueda, A., Lefebvre, F., Wang, Y., Mateo, P., Cassan, C., Gellen, B., Benitah, J. P. and Gomez, A. M.
Reconciling depressed Ca2+ sparks occurrence with enhanced RyR2 activity in failing mice cardiomyocytes
J Gen Physiol (2015)    abstract

Roussel, J., Thireau, J., Brenner, C., Saint, N., Scheuermann, V., Lacampagne, A., Le Guennec, J. Y. and Fauconnier, J.
Palmitoyl-carnitine increases RyR2 oxidation and sarcoplasmic reticulum Ca2+ leak in cardiomyocytes: Role of adenine nucleotide translocase
Biochim Biophys Acta (2015) 1852, 749-758.    abstract

Renet, S., Chaumais, M. C., Antonini, T., Zhao, A., Thomas, L., Savoure, A., Samuel, D., Duclos-Vallee, J. C. and Algalarrondo, V.
Extreme Bradycardia After First Doses of Sofosbuvir and Daclatasvir in Patients Receiving Amiodarone: 2 Cases Including a Rechallenge
Gastroenterology (2015)    abstract

Ramos-Kuri, M., Rapti, K., Mehel, H., Zhang, S., Dhandapany, P. S., Liang, L., Garcia-Carranca, A., Bobe, R., Fischmeister, R., Adnot, S., Lebeche, D., Hajjar, R. J., Lipskaia, L. and Chemaly, E. R.
Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy
Biochim Biophys Acta (2015) 1853, 2870-2884.    abstract

Moulin, M., Piquereau, J., Mateo, P., Fortin, D., Rucker-Martin, C., Gressette, M., Lefebvre, F., Gresikova, M., Solgadi, A., Veksler, V., Garnier, A. and Ventura-Clapier, R.
Sexual dimorphism of doxorubicin-mediated cardiotoxicity: potential role of energy metabolism remodeling
Circ Heart Fail (2015) 8, 98-108.    abstract

Kuum, M., Veksler, V. and Kaasik, A.
Potassium fluxes across the endoplasmic reticulum and their role in endoplasmic reticulum calcium homeostasis
Cell Calcium (2015) 58, 79-85.    abstract

Dominguez-Rodriguez, A., Ruiz-Hurtado, G., Sabourin, J., Gomez, A. M., Alvarez, J. L. and Benitah, J. P.
Proarrhythmic effect of sustained EPAC activation on TRPC3/4 in rat ventricular cardiomyocytes
J Mol Cell Cardiol (2015) 87, 74-78.    abstract

Domingo, D., Neco, P., Fernandez-Pons, E., Zissimopoulos, S., Molina, P., Olague, J., Suarez-Mier, M. P., Lai, F. A., Gomez, A. M. and Zorio, E.
Non-ventricular, Clinical, and Functional Features of the RyR2(R420Q) Mutation Causing Catecholaminergic Polymorphic Ventricular Tachycardia
Rev Esp Cardiol (Engl Ed) (2015) 68, 398-407.    abstract

Crozatier, B. and Ventura-Clapier, R.
Inhibition of hypertrophy, per se, may not be a good therapeutic strategy in ventricular pressure overload: other approaches could be more beneficial
Circulation (2015) 131, 1448-1457.    abstract

Boussabbeh, M., Prola, A., Ben Salem, I., Guilbert, A., Bacha, H., Lemaire, C. and Abis-Essefi, S.
Crocin and quercetin prevent PAT-induced apoptosis in mammalian cells: Involvement of ROS-mediated ER stress pathway
Environ Toxicol (2015) 10.1002/tox.22185.    abstract

Boussabbeh, M., Ben Salem, I., Prola, A., Guilbert, A., Bacha, H., Abid-Essefi, S. and Lemaire, C.
Patulin induces apoptosis through ROS-mediated endoplasmic reticulum stress pathway
Toxicol Sci (2015) 144, 328-337.    abstract

Bisserier, M., Berthouze-Duquesnes, M., Breckler, M., Tortosa, F., Fazal, L., de Regibus, A., Laurent, A. C., Varin, A., Lucas, A., Branchereau, M., Marck, P., Schickel, J. N., Delomenie, C., Cazorla, O., Soulas-Sprauel, P., Crozatier, B., Morel, E., Heymes, C. and Lezoualc'h, F.
Carabin protects against cardiac hypertrophy by blocking calcineurin, Ras, and Ca2+/calmodulin-dependent protein kinase II signaling
Circulation (2015) 131, 390-400; discussion 400.    abstract

Bensassi, F., Gallerne, C., Sharaf el dein, O., Hajlaoui, M. R., Bacha, H. and Lemaire, C.
Combined effects of alternariols mixture on human colon carcinoma cells
Toxicol Mech Methods (2015) 25, 56-62.    abstract

Ben Salem, I., Prola, A., Boussabbeh, M., Guilbert, A., Bacha, H., Abid-Essefi, S. and Lemaire, C.
Crocin and Quercetin protect HCT116 and HEK293 cells from Zearalenone-induced apoptosis by reducing endoplasmic reticulum stress
Cell Stress Chaperones (2015) 10.1007/s12192-12015-10613-12190.    abstract

Algalarrondo, V., Wahbi, K., Sebag, F., Gourdon, G., Beldjord, C., Azibi, K., Balse, E., Coulombe, A., Fischmeister, R., Eymard, B., Duboc, D. and Hatem, S. N.
Abnormal sodium current properties contribute to cardiac electrical and contractile dysfunction in a mouse model of myotonic dystrophy type 1
Neuromuscul Disord (2015) 25, 308-320.    abstract


Bensassi, F., Gallerne, C., Sharaf el Dein, O., Hajlaoui, M. R., Lemaire, C. and Bacha, H.
In vitro investigation of toxicological interactions between the fusariotoxins deoxynivalenol and zearalenone
Toxicon (2014)84, 1-6.    Abstract

Brenner, C. and Lemoine, A.
Mitochondrial Proteins (e.g., VDAC, Bcl-2, HK, ANT) as Major Control Points in Oncology
Front Oncol (2014)4, 365.    Abstract

Cazabat, L., Ragazzon, B., Varin, A., Potier-Cartereau, M., Vandier, C., Vezzosi, D., Risk-Rabin, M., Guellich, A., Schittl, J., Lechêne, P., Richter, W., Nikolaev, V. O., Zhang, J., Bertherat, J. and Vandecasteele, G.
Inactivation of the Carney Complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: A study using genetically-encoded FRET-based reporters
Hum Mol Genet (2014)23, 1163-1174.    Abstract

Clarysse, L., Gueguinou, M., Potier-Cartereau, M., Vandecasteele, G., Bougnoux, P., Chevalier, S., Chantome, A. and Vandier, C.
cAMP-PKA inhibition of SK3 channel reduced both Ca entry and cancer cell migration by regulation of SK3-Orai1 complex
Pflugers Arch (2014)466, 1921-1932.    Abstract

Domingo, D., Neco, P., Fernandez-Pons, E., Zissimopoulos, S., Molina, P., Olague, J., Suarez-Mier, M. P., Lai, F. A., Gomez, A. M. and Zorio, E.
Non-ventricular, clinical, and functional features of the RYR2 mutation causing catecholaminergic polymorphic ventricular tachycardia
Rev Esp Cardiol (Engl Ed) (2014)14, 331-335.    Abstract

Fernandez-Velasco, M., Ruiz-Hurtado, G., Gomez, A. M. and Rueda, A.
Ca2+ handling alterations and vascular dysfunction in diabetes
Cell Calcium (2014)56, 397-407.    Abstract

Galluzzi, L., Vitale, I., Michels, J., Brenner, C., Szabadkai, G., Harel-Bellan, A., Castedo, M. and Kroemer, G.
Systems biology of cisplatin resistance: past, present and future
Cell Death Dis (2014)5, e1257.    Abstract

Guellich, A., Mehel, H. and Fischmeister, R.
Cyclic AMP synthesis and hydrolysis in the normal and failing heart
Pflügers Arch (2014)466, 1163-1175.    Abstract

Haj Slimane, Z., Bedioune, I., Lechêne, P., Varin, A., Lefebvre, F., Mateo, P., Domergue-Dupont, V., Dewenter, M., Richter, W., Conti, M., El-Armouche, A., Zhang, J., Fischmeister, R. and Vandecasteele, G.
Control of cytoplasmic and nuclear protein kinase A activity by phosphodiesterases and phosphatases in cardiac myocytes
Cardiovasc Res (2014)102, 97-106.    Abstract

Hubert, F., Belacel-Ouari, M., Manoury, B., Zhai, K., Domergue-Dupont, V., Mateo, P., Joubert, F., Fischmeister, R. and Leblais, V.
Alteration of vascular reactivity in heart failure: Role of phosphodiesterases type 3 and 4
Br J Pharmacol (2014)171, 5361-5375.    Abstract

Martel, C., Wang, Z. and Brenner, C.
VDAC phosphorylation, a lipid sensor influencing the cell fate
Mitochondrion (2014)19 Pt A, 69-77.    Abstract

Michels, J., Obrist, F., Vitale, I., Lissa, D., Garcia, P., Behnam-Motlagh, P., Kohno, K., Wu, G. S., Brenner, C., Castedo, M. and Kroemer, G.
MCL-1 dependency of cisplatin-resistant cancer cells
Biochem Pharmacol (2014)92, 55-61.    Abstract

Molina, C. E., Johnson, D. M., Mehel, H., Spätjens, R. L. H. M. G., Mika, D., Algalarrondo, V., Haj Slimane, Z., Lechêne, P., Abi-Gerges, N., van der Linde, H. J., Leroy, J., Volders, P. G. A., Fischmeister, R. and Vandecasteele, G.
Interventricular differences in ß-adrenergic responses in the canine heart: Role of phosphodiesterases
J Am Heart Ass (JAHA) (2014)3, e000858.    Abstract

Monceau, V., Llach, A., Azria, D., Bridier, A., Petit, B., Mazevet, M., Strup-Perrot, C., To, T. H., Calmels, L., Germaini, M. M., Gourgou, S., Fenoglietto, P., Bourgier, C., Gomez, A. M., Escoubet, B., Dorr, W., Haagen, J., Deutsch, E., Morel, E. and Vozenin, M. C.
Epac contributes to cardiac hypertrophy and amyloidosis induced by radiotherapy but not fibrosis
Radiother Oncol (2014)111, 63-71.    Abstract

Montani, D., Chaumais, M. C., Guignabert, C., Gunther, S., Girerd, B., Jais, X., Algalarrondo, V., Price, L. C., Savale, L., Sitbon, O., Simonneau, G. and Humbert, M.
Targeted therapies in pulmonary arterial hypertension
Pharmacol Ther (2014)141, 172-191.    Abstract

Pereira, L., Ruiz-Hurtado, G., Rueda, A., Mercadier, J. J., Benitah, J. P. and Gomez, A. M.
Calcium signaling in diabetic cardiomyocytes
Cell Calcium (2014)56, 372-380.    Abstract

Previlon, M., Pezet, M., Vinet, L., Mercadier, J. J. and Rouet-Benzineb, P.
Gender-specific potential inhibitory role of Ca2+/calmodulin dependent protein kinase phosphatase (CaMKP) in pressure-overloaded mouse heart
PLoS One (2014)9, e90822.    Abstract

Tufo, G., Jones, A. E. W., Wang Z, Tajeddine, N., Hamelin, J., Degli Esposti, D., Martel, C., Boursier, C., Gallerne, C., Migdal, C., Lemaire, C., Szabadkai, G., Lemoine, A., Kroemer, G. and Brenner, C.
The protein disulfide isomerases PDIA4 and A6 mediate resistance to cisplatin-induced cell death in lung adenocarcinoma
Cell Death Diff (2014)21, 685-695.    Abstract

Unsöld, B., Kaul, A., Sbroggiò, M., Schubert, C., Regitz-Zagrosek, V., Brancaccio, M., Damilano, F., Hirsch, E., van Bilsen, M., Munts, C., Sipido, K., Bito, V., Detre, V., Wagner, N. M., Schäfer, K., Seidler, T., Vogt, J., Neef, S., Bleckmann, A., Maier, L. S., Balligand, J. L., Bouzin, C., Ventura-Clapier, R., Garnier, A., Eschenhagen, T., El-Armouche, A., Knöll, R., Tarone, G. and Hasenfuß, G.
Melusin protects from cardiac rupture and improves functional remodeling after myocardial infarction
Cardiovasc Res (2014)101, 97-107.    Abstract

Wojewoda, M., Kmiecik, K., Ventura-Clapier, R., Fortin, D., Onopiuk, M., Jakubczyk, J., Sitek, B., Fedorowicz, A., Majerczak, J., Kaminski, K., Chlopicki, S. and Zoladz, J. A.
Running performance at high running velocities is impaired but VO2max and peripheral endothelial function are preserved in the IL-6-/- mice
PLoS One (2014)9, e88333.    Abstract

Zhai, K., Chang, Y., Wei, B., Liu, Q., Leblais, V., Fischmeister, R. and Ji, G.
Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms
Cell Signal (2014)26, 1001-1010.    Abstract


  Algalarrondo, V., Boycott, H., Eliahou, L., Mabille, M., & Slama, M. S.
Indications of anti-inflammatory drugs in cardiac diseases.
Antiinflamm Antiallergy Agents Med Chem. (2013) 12, 3-13     Abstract

Belge, C., Hammond, J., Dubois-Deruy, E., Manoury, B., Hamelet, J., Beauloye, C., Markl, A., Pouleur, A. C., Bertrand, L., Esfahani, H., Jnaoui, K., Götz, K. R., Nikolaev, V. O., Vanderper, A., Herijgers, P., Lobysheva, I., Iaccarino, G., Hilfiker-Kleiner, D., Tavernier, G., Langin, D., Dessy, C., & Balligand, J. L.
Enhanced expression of ß3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.
Circulation. (2013),     Abstract

Bito, V., Biesmans, L., Gellen, B., Antoons, G., Macquaide, N., Rouet-Benzineb, P., Pezet, M., Mercadier, J. J., & Sipido, K. R.
FKBP12.6 overexpression does not protect against remodelling after myocardial infarction.
Exp Physiol. (2013) 98, 134-148     Abstract

Brenner, C., Galluzzi, L., Kepp, O., & Kroemer, G.
Decoding cell death signals in liver inflammation.
J Hepatol. (2013) 59, 583-594     Abstract

Caffin, F., Prola, A. P., J., Novotova, M., David, D. J., Garnier, A., Fortin, D., Alavi, M., Veksler, V., Ventura-Clapier, R., & Joubert, F.
Altered skeletal muscle mitochondrial biogenesis but improved endurance capacity in trained OPA1-deficient mice.
J Physiol - London. (2013),     Abstract

Cagalinec, M., Safiulina, D., Liiv, M., Liiv, J., Choubey, V., Wareski, P., Veksler, V., & Kaasik, A.
Principles of the mitochondrial fusion and fission cycle in neurons.
J Cell Sci. (2013) 126, 2187-2197     Abstract

Chargari, C., Riet, F., Mazevet, M., Morel, E., Lepechoux, C., & Deutch, E.
Complications of thoracic radiotherapy.
Quarterly Medical Review. (2013) 42 e352–e361     Abstract

Courilleau, D., Bouyssou, P., Fischmeister, R., Blondeau, J. P., & Lezoualc’h, F.
The (R)-enantiomer of CE3F4 is a preferential inhibitor of human exchange protein directly activated by cyclic AMP isoform 1 (Epac1).
Biochem Biophys Res Commun. (2013) 440, 443-448     Abstract

Gallerne, C., Prola, A., & Lemaire, C.
Hsp90 inhibition by PU-H71 induces apoptosis through endoplasmic reticulum stress and mitochondrial pathway in cancer cells and overcomes the resistance conferred by Bcl-2.
BBA - Mol Cell Res. (2013)1833, 1356-1366     Abstract

Gena, P., Mastrodonato, M., Portincasa, P., Fanelli, E., Mentino, D., Rodríguez, A., Marinelli, R. A., Brenner, C., Frühbeck, G., Svelto, M., & Calamita, G.
Liver glycerol permeability and Aquaporin-9 are dysregulated in a murine model of Non-Alcoholic Fatty Liver Disease.
PlOS One. (2013), (in press)     Abstract

Gómez, A. M., Ruiz-Hurtado, G., Benitah, J. P., & Domínguez-Rodríguez, A.
Ca2+ fluxes involvement in gene expression during cardiac hypertrophy.
Curr Vasc Pharmacol. (2013) 11, 497-506     Abstract

Guellich, A., Damy, T., Conti, M., Claes, V. A., Samuel, J. L., Pineau, T., Lecarpentier, Y., & Coirault, C.
Tempol prevents cardiac oxidative damage and left ventricular dysfunction in the PPAR-alpha KO mouse.
Am J Physiol Heart Circ Physiol. (2013) 304, H1505-1512     Abstract

Lally, J. S., Herbst, E. A., Matravadia, S., Maher, A. C., Perry, C. G., Ventura-Clapier, R., & Holloway, G. P.
Over-expressing mitofusin-2 in healthy mature mammalian skeletal muscle does not alter mitochondrial bioenergetics.
PlOS One. (2013) 8, e55660     Abstract

Lefebvre, J., Muharram, G., Leroy, C., Ichim, G., Tauszig-Delamasure, S., Chotteau-Lelievre, A., Brenner, C., Mehlen, P., & Tulasne, D.
Caspase-generated fragment of the Met receptor favors apoptosis via the intrinsic pathway independently of its tyrosine kinase activity.
Cell Death Dis. (2013),     Abstract

Martel, C., Allouche, M., Esposti, D. D., Fanelli, E., Boursier, C., Henry, C., Chopineau, J., Calamita, G., Kroemer, G., Lemoine, A., & Brenner, C.
Glycogen synthase kinase 3-mediated voltage-dependent anion channel phosphorylation controls outer mitochondrial membrane permeability during lipid accumulation.
Hepatology. (2013) 57, 93-102     Abstract

Mazevet, M., Moulin, M., Llach-Martinez, A., Chargari, C., Deutsch, E., Gomez, A. M., & E., M.
Complications of chemotherapy, a basic science update.
Quarterly Medical Review. (2013) 42, e342-e351     Abstract

Mehel, H., Emons, J., Vettel, C., Wittköpper, K., Seppelt, D., Dewenter, M., Lutz, L., Sossalla, S., Maier, L. S., Lechêne, P., Leroy, J., Lefebvre, F., Varin, A., Eschenhagen, T., Nikolaev, V. O., Zimmermann, W. H., Vandecasteele, G., Fischmeister, R., & El-Armouche, A.
Phoshodiesterase-2 is upregulated in human failing hearts and blunts? Adrenergic responses in cardiomyocytes.
J Am Coll Cardiol. (2013) 62, 1596-1606     Abstract

Michels, J., Vitale, I., Galluzzi, L., Adam, J., Olaussen, K. A., Kepp, O., Senovilla, L., Talhaoui, I., Guegan, J., Enot, D. P., Talbot, M., Robin, A., Girard, P., Orear, C., Lissa, D., Sukkurwala, A. Q., Garcia, P., Behnam-Motlagh, P., Kohno, K., Wu, G. S., Brenner, C., Dessen, P., Saparbaev, M., Soria, J. C., Castedo, M., & Kroemer, G.
Cisplatin resistance associated with PARP hyperactivation.
Cancer Res. (2013) 73, 2271-2280     Abstract

Michels, J., Vitale, I., Senovilla, L., Enot, D. P., Garcia, P., Lissa, D., Olaussen, K. A., Brenner, C., Soria, J. C., Castedo, M., & Kroemer, G.
Synergistic interaction between cisplatin and PARP inhibitors in non-small cell lung cancer.
Cell Cycle. (2013) 12, 877-883     Abstract

Mika, D., Bobin, P., Pomérance, M., Lechêne, P., Westenbroek, R., Catterall, W. A., Vandecasteele, G., Leroy, J., & Fischmeister, R.
Differential regulation of cardiac excitation-contraction coupling by cAMP phosphodiesterase subtypes.
Cardiovasc Res. (2013) 100, 336-346     Abstract

Monceau, V., Meziani, L., Strup-Perrot, C., Morel, E., Schmidt, M., Haagen, J., Escoubet, B., Dorr, W., & Vozenin, M. C.
Enhanced sensitivity to low dose irradiation of ApoE-/- mice mediated by early pro-inflammatory profile and delayed activation of the Tgf b1 cascade involved in fibrogenesis.
PlOS One. (2013) 8     Abstract

Piquereau, J., Caffin, F., Novotova, M., Lemaire, C., Veksler, V., Garnier, A., Ventura-Clapier, R., & Joubert, F.
Mitochondrial dynamics in the adult cardiomyocytes: which roles for a highly specialized cell?
Front Physiol. (2013) 4, 102     Abstract

Robin, E., Sabourin, J., Marcillac, F., & Raddatz, E.
Involvement of CD73, equilibrative nucleoside transporters and inosine in rhythm and conduction disturbances mediated by adenosine A1 and A2a receptors in the developing heart.
J Mol Cell Cardiol. (2013) 63C, 14-25     Abstract

Rueda, A., Fernandez-Velasco, M., Benitah, J. P., & Gomez, A. M.
Abnormal Ca2+ spark/STOC coupling in cerebral artery smooth muscle cells of obese type 2 diabetic mice.
PlOS One. (2013) 8, e53321     Abstract

Ruiz-Hurtado, G., Morel, E., Dominguez-Rodriguez, A., Llach, A., Lezoualc'h, F., Benitah, J. P., & Gomez, A. M.
Epac in cardiac calcium signaling.
J Mol Cell Cardiol. (2013) 58, 162-171     Abstract

Schulz, S., Schmitt, S., Wimmer, R., Aichler, M., Eisenhofer, S., Lichtmannegger, J., Eberhagen, C., Artmann, R., Tookos, F., Walch, A., Krappmann, D., Brenner-Jan, C., Rust, C., & Zischka, H.
Progressive stages of mitochondrial destruction caused by celltoxic bile salts.
BBA - Biomembranes. (2013) 1828, 2121-2133     Abstract

Tritsch, E., Mallat, Y., Lefebvre, F., Diguet, N., Escoubet, B., Blanc, J., De Windt, L., Catalucci, D., Vandecasteele, G., Li, Z., & Mericskay, M.
An SRF/miR-1 axis regulates NCX1 and annexin A5 protein levels in the normal and failing heart.
Cardiovasc Res. (2013) 98, 372-380     Abstract

Unsöld, B., Kaul, A., Sbroggiò, M., Schubert, C., Regitz-Zagrosek, V., Brancaccio, M., Damilano, F., Hirsch, E., van Bilsen, M., Munts, C., Sipido, K., Bito, V., Detre, V., Wagner, N. M., Schäfer, K., Seidler, T., Vogt, J., Neef, S., Bleckmann, A., Maier, L. S., Balligand, J. L., Bouzin, C., Ventura-Clapier, R., Garnier, A., Eschenhagen, T., El-Armouche, A., Knöll, R., Tarone, G., & Hasenfuß, G.
Melusin protects from cardiac rupture and improves functional remodeling after myocardial infarction.
Cardiovasc Res. (2013),     Abstract

Van Berendoncks, A. M., Garnier, A., Ventura-Clapier, R., & Conraads, V. M.
Adiponectin: key role and potential target to reverse energy wasting in chronic heart failure.
Heart Fail Rev. (2013),     Abstract

Villeneuve, C., Guilbeau-Frugier, C., Sicard, P., Lairez, O., Ordener, C., Duparc, T., De Paulis, D., Couderc, B., Spreux-Varoquaux, O., Tortosa, F., Garnier, A., Knauf, C., Valet, P., Borchi, E., Nediani, C., Gharib, A., Ovize, M., Delisle, M. B., Parini, A., & Mialet-Perez, J.
p53-PGC-1a pathway mediates oxidative mitochondrial damage and cardiomyocyte necrosis induced by monoamine oxidase-A upregulation: Role in chronic left ventricular dysfunction in mice.
Antioxid Redox Signal. (2013) 18, 5-18     Abstract

Zhang, H., Gomez, A. M., Wang, X., Yan, Y., Zheng, M., & Cheng, H.
ROS regulation of microdomain Ca 2+ signalling at the dyads.
Cardiovasc Res. (2013) 98, 248-258     Abstract


Bensassi, F., Gallerne, C., El Dein, O. S., Hajlaoui, M. R., Bacha, H. & Lemaire, C..
Cell death induced by the Alternaria mycotoxin Alternariol.
Toxicol In Vitro. (2012) 6, 915-23.   Abstract

Bensassi, F., Gallerne, C., El Dein, O. S., Lemaire, C., Hajlaoui, M. R. & Bacha, H.
Involvement of Mitochondria-Mediated Apoptosis in Deoxynivalenol Cytotoxicity.
Food and Chemical Toxicology (2012)50, 1680-1689.   Abstract

Brenner, C., Moulin, M.
Physiological roles of the permeability transition pore.
Circulation Research (2012)111, 1237-1247.   Abstract

Courilleau, D., Bisserier, M., Jullian, J. C., Lucas, A., Bouyssou, P., Fischmeister, R., Blondeau, J. P. & Lezoualc’h, F.
Identification of a tetrahydroquinoline analog as a pharmacological inhibitor of the cAMP-binding protein Epac.
Journal of Biological Chemistry (2012)53, 44192-202.   Abstract

Domínguez-Rodríguez A., Díaz I., Rodríguez-Moyano M., Calderón-Sánchez E., Rosado JA., Ordóñez A. & Smani T.
Urotensin-II signaling mechanism in rat coronary artery: role of STIM1 and Orai1-dependent store operated calcium influx in vasoconstriction .
Arteriosclerosis Thrombosis Vascular Biology (2012)32, 1325-1332.   Abstract

Domínguez-Rodríquez, A., Ruiz-Hurtado, G., Benitah, J. P. & Gomez, A. M.
The other side of cardiac Ca2+ signaling: transcriptional control.
Frontiers in Computational Physiology and Medicine (2012)3, 452.   Abstract

Ghigo, A., Perino, A., Mehel, H., Zahradnikova, A. Jr., Morello, F., Leroy, J., Nikolaev, V. O., Damilano, F., Cimino, J., De Luca, E., Richter, W., Westenbroek, R., Catterall, W. A., Zhang, J., Yan, C., Conti, M., Gomez, A. M., Vandecasteele, G., Hirsch, E. & Fischmeister, R.
PI3KY protects against catecholamine-induced ventricular arrhythmia through PKA-mediated regulation of distinct phosphodiesterases.
Circulation (2012)126, 2073-1083.   Abstract

Gibert, B., Eckel, B., Fasquelle, L., Moulin, M., Bouhallier, F., Gonin, V., Mellier, G., Simon, S., Kretz-Remy, C., Arrigo, A. P. & Diaz-Latoud, C.
Knock down of heat shock protein 27 (Hspb1) induces degradation of several putative client proteins.
PloS One (2012)7, e29719 .   Abstract

Izem-Meziane, M., Djerdjouri, B., Rimbaud, S., Caffin, F., Fortin, D., Garnier, A., Veksler, V., Joubert, F. & Ventura-Clapier, R.
Catecholamine-Induced Cardiac Mitochondrial Dysfunction and Mptp Opening: Protective Effect of Curcumin.
American Journal of Physiology-Heart and Circulatory Physiology (2012)302, H665-H674.   Abstract

Janiek, R., Zahradnikova, A., Polakova, E., Pavelkova, J., Zahradnik, I. & Zahradnikova, A.
Calcium spike variability in cardiac myocytes results from activation of small cohorts of ryanodine receptor 2 channels.
Journal of Physiology-London (2012)590, 5091-5106.   Abstract

Joly-Amado, A., Denis, R. G., Castel, J., Lacombe, A., Cansell, C., Rouch, C., Kassis, N., Dairou, J., Cani, P. D., Ventura-Clapier, R., Prola, A., Flamment, M., Foufelle, F., Magnan, C. & Luquet, S.
Hypothalamic AgRP-neurons control peripheral substrate utilization and nutrient partitioning.
EMBO Journal (2012)22, 4276-88.   Abstract

Kuum, M., Veksler, V., Liiv, J., Ventura-Clapier, R. & Kaasik, A.
Endoplasmic Reticulum Potassium-Hydrogen Exchanger and Small Conductance Calcium-Activated Potassium Channel Activities Are Essential for Er Calcium Uptake in Neurons and Cardiomyocytes.
Journal of Cell Science (2012)125, 625-633.   Abstract

Lecoeur, H., Borgne-Sanchez, A., Chaloin, O., El-Khoury, R., Brabant, M., Langonne, A., Porceddu, M., Briere, J. J., Buron, N., Rebouillat, D., Pechoux, C., Deniaud, A., Brenner, C., Briand, J. P., Muller, S., Rustin, P. & Jacotot, E.
Hiv-1 Tat Protein Directly Induces Mitochondrial Membrane Permeabilization and Inactivates Cytochrome C Oxidase.
Cell Death & Disease (2012)3, e282.   Abstract

Martel, C., Degli Esposti, D., Bouchet, A., Brenner, C. & Lemoine, A.
Non-Alcoholic Steatohepatitis: New Insights From Omics Studies.
Current Pharmaceutical Biotechnology (2012)13, 726-735.   Abstract

Martel, C., Huynh le, H., Garnier, A., Ventura-Clapier, R. & Brenner, C.
Inhibition of the mitochondrial permeability transition for cytoprotection: Direct versus indirect mechanisms.
Biochemical Research International (2012), 213403.   Abstract

Mika, D., Leroy, J., Vandecasteele, G. & Fischmeister, R.
Pdes Create Local Domains of Camp Signaling.
Journal of Molecular and Cellular Cardiology (2012)52, 323-329.   Abstract

Mika, D., Leroy, J., Vandecasteele, G. & Fischmeister, R.
Rôle des phosphodiestérases des nucléotides cycliques dans la compartimentation subcellulaire de l’AMP cyclique des myocytes cardiaques.
Biologie Aujourd'hui (2012)206, 11-24.   Abstract

Molina, C. E., Leroy, J., Richter, W., Xie, M., Scheitrum, C., Lee, I. O., Maack, C., Rucker-Martin, C., Donzeau-Gouge, P., Verde, I., Llach, A., Hove-Madsen, L., Conti, M., Vandecasteele, G. & Fischmeister, R.
Cyclic adenosine monophosphate phosphodiesterase type 4 protects against atrial arrhythmias.
J Am Coll Cardiol (2012)59, 2182-90.   Abstract

Mosbah, I. B., Zaouali, M. A., Martel, C., Bjaoui, M., Abdennebi, H. B., Hotter, G., Brenner, C. & Rosello-Catafau, J.
Igl-1 Solution Reduces Endoplasmic Reticulum Stress and Apoptosis in Rat Liver Transplantation.
Cell Death & Disease (2012)3, e279.   Abstract

Moulin, M., Anderton, H., Voss, A. K., Thomas, T., Wong, W. W. L., Bankovacki, A., Feltham, R., Chau, D., Cook, W. D., Silke, J. & Vaux, D. L.
Iaps limit activation of Rip kinases by Tnf receptor 1 during development.
EMBO Journal (2012)31, 1679-1691.   Abstract

Neco, P., Torrente, A. G., Mesirca, P., Zorio, E., Liu, N., Priori, S. G., Napolitano, C., Richard, S., Benitah, J. P., Mangoni, M. E. & Gomez, A. M.
Paradoxical Effect of Increased Diastolic Ca2+ Release and Decreased Sinoatrial Node Activity in a Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia.
Circulation (2012)126, 392-401.   Abstract

N’Guessan, B. B., Sanchez, H., Zoll, J., Ribera, F., Dufour, S., Lampert, E., Kindo, M., Geny, B., Ventura-Clapier, R. & Mettauer, B.
Oxidative capacities of cardiac and skeletal muscles of heart transplant recipients: mitochondrial effects of cyclosporin-A and its vehicle Cremophor-EL.
Fundamental and Clinical Pharmacology (2012).   Abstract

Pereira, L., Ruiz-Hurtado, G., Morel, E., Laurent, A. C., Metrich, M., Dominguez-Rodriguez, A., Lauton-Santos, S., Lucas, A., Benitah, J. P., Bers, D. M., Lezoualc'h, F. & Gomez, A. M.
Epac Enhances Excitation-Transcription Coupling in Cardiac Myocytes.
Journal of Molecular and Cellular Cardiology (2012)52, 283-291.   Abstract

Piquereau, J., Caffin, F., Novotova, M., Prola, A., Garnier, A., Mateo, P., Fortin, D., Huynh, L. H., Nicolas, V., Alavi, M. V., Brenner, C., Ventura-Clapier, R., Veksler, V. & Joubert, F.
Down-Regulation of Opa1 Alters Mouse Mitochondrial Morphology, Ptp Function, and Cardiac Adaptation to Pressure Overload.
Cardiovascular Research (2012)94, 408-417.   Abstract

Ruiz-Hurtado, G., Dominguez-Rodriguez, A., Pereira, L., Fernandez-Velasco, M., Cassan, C., Lezoualc'h, F., Benitah, J. P. & Gomez, A. M.
Sustained Epac activation induces calmodulindependent positiveinotropic effect in adult cardiomyocytes.
Journal of Molecular and Cellular Cardiology (2012)53, 617-625.   Abstract

Ruiz-Hurtado, G., Gomez-Hurtado, N., Fernandez-Velasco, M., Calderon, E., Smani, T., Ordonez, A., Cachofeiro, V., Bosca, L., Diez, J., Gomez, A. M. & Delgado, C.
Cardiotrophin-1 induces sarcoplasmic reticulum Ca-2 leak and arrhythmogenesis in adult rat ventricular myocytes.
Cardiovascular Research (2012)96, 81-89.   Abstract

Ruiz, M., Courilleau, D., Jullian, J. C., Fortin, D., Ventura-Clapier, R., Blondeau, J. P. & Garnier, A.
A cardiac-specific robotized cellular assay identified families of human ligands as inducers of PGC1-alpha expression and mitochondrial biogenesis.
PloS One (2012)7, e46753.   Abstract

Sabourin, J., Antigny, F., Robin, E., Frieden, M. & Raddatz, E.
Activation of transient receptor potential canonical 3 (Trpc3)-mediated Ca2+ entry by a(1) adenosine receptor in cardiomyocytes disturbs atrioventricular conduction.
Journal of Biological Chemistry (2012)287, 26688-26701.   Abstract

Sabourin J., Harisseh R., Harnois T., Magaud C., Bourmeyster N., Déliot N. & Constantin B.
Dystrophin/á1-syntrophin scaffold regulated PLC/PKC-dependent store-operated calcium entry in myotubes.
Cell Calcium (2012)52, 445-56.   Abstract

Sharaf El Dein, O., Gallerne, C., Brenner, C. & Lemaire, C.
Increased Expression of Vdac1 Sensitizes Carcinoma Cells to Apoptosis Induced by Dna Cross-Linking Agents.
Biochemical Pharmacology (2012)83, 1172-1182.   Abstract

Van Berendoncks, A. M., Garnier, A., Ventura-Clapier, R. & Conraads, V. M.
Adiponectin: key role and potential target to reverse energy wasting in chronic heart failure.
Heart Failure (2012).   Abstract

Ventura-Clapier R
Molecular mechanisms of exercise physiology. Cardaic hypertrophy, pathological.
Encyclopedia of Exercise Medicine in Health and disease Mooren, Frank C. (Ed.) (2012)

Vergeade, A., Mulder, P., Vendeville, C., Ventura-Clapier, R., Thuillez, C. & Monteil, C.
Xanthine oxidase contributes to mitochondrial ROS generation in an experimental model of cocaine-induced diastolic dysfunction.
J Cardiovasc Pharmacol. (2012).   Abstract

Vinet, L., Pezet, M., Bito, V., Briec, F., Biesnians, L., Rouet-Benzineb, P., Gellen, B., Previlon, M., Chimenti, S., Vilaine, J. P., Charpentier, F., Sipido, K. R. & Mercadier, J. J.
Cardiac Fkbp12.6 overexpression protects against triggered ventricular tachycardia in pressure overloaded mousehearts.
Basic Research in Cardiology (2012)107, 246.   Abstract

Zhai, K., Hubert, F., Nicolas, V., Ji, G., Fischmeister, R. & Leblais, V.
ß-Adrenergic cAMP signals are predominantly regulated by phosphodiesterase type 4 in cultured adult rat aortic smooth muscle cells.
PloS One (2012)7, e47826.   Abstract